2004 Spinout of the Year

Cellective Therapeutics, Inc.

Description

RTP-based Cellective Therapeutics, Inc., develops new therapies for autoimmunity disorders and B cell related cancers. Autoimmune disorders – which include rheumatoid arthritis, systemic lupus erythematosus (SLE), and multiple sclerosis – afflict over 50 million people in the United States. Non-Hodgkin’s lymphoma is one of the most commonly diagnosed cancers in the United States. Cellective’s technology utilizes breakthrough B cell directed monoclonal antibody therapies developed by Dr. Thomas F. Tedder, Chairman of the Department of Immunology at Duke University.

Reasons for winning the award

Cellective Therapeutics was born out of world-class research at Duke University on autoimmunity disorders. Since spinning out of Duke, Cellective has secured a strong management team, financial backing, and scientific expertise on its early path to success.

Quote

“A new company requires an environment with a rich sense of community, with enthusiasm for entrepreneurship, and with a healthy appetite for risk and growth. The RTP is the perfect home for Cellective, and we are proud to be recognized as a great example of what can be achieved here. We thank CED for the essential role it plays in creating such an environment for all of us.” -- Lisa Beth Ferstenberg, President and CEO, Cellective Therapeutics

History

Dr. Tedder, Cellective’s scientific founder, first identified the relationship between B cells and autoimmune diseases. Cellective’s technology is based on his breakthrough discoveries. C ellective, which was incorporated in May 2003, is a portfolio company of Durham-based Intersouth Partners. Cellective’s experienced management team is headed by Lisa Beth Ferstenberg, M.D., a seasoned biopharmaceutical professional with more than 20 years’ experience developing and commercializing oncology and immunology products. The company’s clinical trials will be overseen by the Chairman of its Clinical Consortium, William St. Clair, M.D., who is Principal Investigator of Duke University’s Academic Center of Excellence for Autoimmunity, and a leader of the national clinical consortium, The Immune Tolerance Network.

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