Cary-based Trana Discovery (www.tranadiscovery.com), a drug discovery firm, and the Southern Research Institute have agreed to work together to seek potential drugs for the treatment of AIDS. Under the agreement, Trana will screen Southern Research’s extensive collection of nucleosides to identify antiinfectives with a novel mechanism of action.
Trana Discovery technology can help discover innovative classes of anti-infective compounds found in chemical libraries held by partner organizations. Trana's screening assays identify compounds that interrupt the lifecycle of pathogens through a new mechanism of action—the inhibition of transfer RNA (tRNA).