Venture 2006 Presenting Companies

Early Stage Presenters

Advanced Liquid Logic, Inc. Bioptigen Broadwick Corporation Emu Software Ercole Biotech INI Power Systems, Inc.

Phase Bioscience, Inc. Pique Therapeutics, Inc. Optotrack, Inc. Teotten Diagnostics Visitar, Inc. ZinkKat

Main Stage Presenters

Argos Therapeutics, Inc. Arrendale Associates Bright View Technologies Centice Corporation Kyma Technologies, Inc. Liquidia Technologies, Inc. Nextreme Thermal Solutions, Inc.

Nitronex Corporation Overture Networks Piedmont Pharmaceuticals rPath SCYNEXIS, Inc. Xsira Pharmaceuticals, Inc.

Showcase Companies

Integrian, Inc. TranS1, Inc.

Early Stage Presenters

Advanced Liquid Logic, Inc. (RTP, NC - www.liquid-logic.com) Advanced Liquid Logic is developing patented microfluidic technology for portable lab-on-a-chip systems. This technology offers the opportunity for miniaturizing and automating an enormous array of liquid-based laboratory, medical, and other analyses.

[ Top ]

Bioptigen (Durham, NC - www.bioptigen.com) Bioptigen is advancing non-invasive 3D optical imaging systems for pre-clinical pharma, biotech and biomedical applications. Bioptigen technology significantly reduces the need for surgical histology in pre-clinical ophthalmology, drug efficacy and toxicology testing, and offers unmatched dynamic imaging capabilities for functional genomics and tissue engineering research.

[ Top ]

Broadwick Corporation (Durham, NC - www.broadwick.com) Broadwick is a provider of leading email communications software. Broadwick's flagship product, IntelliContact, allows small businesses and associations to easily create, send, and track permission-based email newsletters, promotions, announcements, and surveys. Its enterprise-level offering, IntelliCampaign, allows Fortune 500® and public to build stronger relationships with their customers and prospects and manage one-to-many corporate email communications.

[ Top ]

Emu Software (Cary, NC - www.emusoftware.com) Emu Software is a Linux Server Configuration Management Software Provider. The company's NetDirector product allows businesses to easily migrate to Linux - without adding additional staff or expertise. NetDirector enables enterprises and service providers alike to benefit from the power of Linux with the simplicity of Windows.

[ Top ]

Ercole Biotech (RTP, NC - www.ercolebiotech.com) Ercole Biotech creates and develops drugs that direct splicing of messenger RNA. Ercole's therapeutics are designed to alter pre-mRNA splicing and can be used to up-regulate or downregulate protein expression, switch gene expression from one protein isoform to another, and restore function to defective genes. [Listen to this company’s audio interview.]

[ Top ]

INI Power Systems, Inc. (Cary, NC - www.inipower.com) INI Power Systems is a developer of Portable Power Fuel Cell Systems. INI Power Systems has pioneered the Direct Methanol Laminar Flow Fuel Cell to provide an inherently high performance micro power system directed at replacing current battery technologies used in portable consumer electronics (laptop computers, PDAs, entertainment devices, etc).

[ Top ]

Phase Bioscience, Inc. (Durham, NC - www.phasebio.com) PhaseBio is revolutionizing the purification of biotherapeutics through innovative technology that enables recombinant peptide and protein therapeutics production without chromatography. PhaseBio's deltaPhaseT System incorporates a novel, patented technology for expression and purification of recombinant peptides and proteins using a class of biopolymers called elastin-like polypeptides.

[ Top ]

Pique Therapeutics, Inc. (Durham, NC - www.piquetherapeutics.com) is a biotechnology company seeking to become the leader in therapeutic vaccines, focused initially on the treatment of cancer. The company's lead product is a first-in-class therapeutic vaccine for non-small cell lung cancer and has completed Phase 1 clinical trials. Pique's novel technology affords it the opportunity to create therapeutic vaccines for many additional areas of oncology, such as pancreatic cancer, colon cancer, and head and neck cancer.

[ Top ]

Optotrack, Inc. (Cary, NC - www.optotrack.com) Optotrack is a provider of microfluidic chips, sensor arrays, and microsystems. Optotrack's precision fabrication technology addresses a variety of applications including microfluidics, MEMS, solid-state sensing, and biochemical analysis. It permits the low-cost fabrication of very precise structures from a broad range of engineering materials. [Listen to this company’s audio interview.]

[ Top ]

Teotten Diagnostics (RTP, NC - www.teotten.com) Teotten Diagnostics is developing unique diagnostics for life-threatening infectious diseases associated with central venous catheter use, and with other hospital acquired (nosocomial) infections. The company's first products will be diagnostic tests for invasive fungal infections based upon a proprietary technology for the detection of pathogen specific compounds in blood. [Listen to this company’s audio interview.]

[ Top ]

Visitar, Inc. (Raleigh, NC - www.visitar.com) Visitar (formerly AppCentrex) provides leading, affordable hosted services for communications-enabled business applications. The company's “Solutions as a Service” model includes a robust suite of software applications that can be configured by the end user to optimally fit their unique business needs.

[ Top ]

ZinkKat (Cary, NC - www.zinkkat.com) ZinkKat designs, builds and distributes integrated, wireless terminals that enable seamless migration among communications, entertainment and web-based channels. Zinkkat’s first product, Chili, is a unique consumer product that integrates entertainment, communications and the Internet within an easy-to-use, hiptop wireless device.

[ Top ]

Main Stage Presenters

Argos Therapeutics, Inc. (Durham, NC - www.argostherapeutics.com) Argos Therapeutics is developing therapeutic options in the rapidly-growing field of dendritic cell research and development. The company is dedicated to becoming a market leader in the field of immunotherapy by using proprietary technology and know-how to develop dendritic cell-based therapies in the areas of oncology, infectious diseases, autoimmune disorders and transplantation.

[ Top ]

Arrendale Associates (Cornelius, NC - www.aaita.com) Arrendale Associates is a software company focusing on medical transcription workflow and document management solutions. The company provides a comprehensive suite of installed and web-based (ASP) solutions which enable and facilitate the outsourcing and off-shoring of medical transcription for hospitals and the medical transcription service organizations (MTSOs) that serve them.

[ Top ]

Bright View Technologies (Morrisville, NC - www.brightviewtechnologies.com) Bright View Technologies is a leading developer of innovative, microstructure based, optical films for the global display industry. Bright View is leveraging a unique and proprietary platform technology, X-LAMPS, that enables the creation of highly engineered plastic films with superior light management characteristics.

[ Top ]

Centice Corporation (Durham, NC - www.centice.com) Centice Corporation is commercializing a patent-pending computational sensor technology originally developed at Duke University. Centice leverages this technology with its expertise in instrument design to produce a portfolio of high sensitivity optical sensing modules for the analytical, life sciences, medical and pharmaceutical industries.

[ Top ]

Kyma Technologies, Inc. (Raleigh, NC - www.kymatech.com) Kyma Technologies is an advanced semiconductor materials and device supplier. Kyma's patented single-crystal native gallium nitride (GaN) materials represents a new materials platform technology which will enable broad commercialization of multiple next generation semiconductor device technologies with over $30B total market potential based on a broad range of applications including data storage, high power electronics, biological and chemical sensors, solid state lighting, and wireless communications.

[ Top ]

Liquidia Technologies, Inc. (RTP, NC - www.liquidia.com) Liquidia Technologies seeks to commercialize a series of technologies developed in the labs of Professors Joseph DeSimone and Edward Samulski at the University of North Carolina at Chapel Hill. Through strategic partnerships and licensing agreements these technologies are poised to revolutionize the fields of microfluidics, soft-lithography, and nanoparticle applications, including drug delivery and discovery. The core of the technology involves the use of novel solvent-resistant, moldable materials that enable imprinting applications for micro and nano-features.

[ Top ]

Nextreme Thermal Solutions, Inc. (RTP, NC - www.nextremethermal.com) Nextreme Thermal Solutions develops high performance, thin-film, embedded thermoelectric components (eTECs) for semiconductor hot spot cooling and energy harvesting applications. The company's unique superlattice technology provides the embedding of an active cooling device directly into an integrated circuit or its package. Other applications include converting heat into electricity for advanced power generation applications, thermal batteries and automotive energy management.

[ Top ]

Nitronex Corporation (Raleigh, NC - www.nitronex.com) Nitronex Corporation, an integrated device manufacturer (“IDM”), is a privately held developer of advanced Gallium Nitride (GaN) materials and process technology. Built on industry standard silicon (“Si”) substrates and using the world's first commercial-grade GaN-on-Silicon semiconductor process, the Company's proprietary solutions leverage the unique properties of GaN and the low-cost manufacturing capabilities of silicon to provide high-performance, high-power semiconductors to the commercial wireless infrastructure, power management and military markets. [Listen to this company’s audio interview.]

[ Top ]

Overture Networks (Morrisville, NC - www.overturenetworks.com) Overture Networks enables network service providers to move towards a packet-based network that can keep pace with the increasing need for intelligence and speed at the edge of the network. With the ISG family of converged packet access solutions, carriers can deliver new data and voice services over both today's networks and the networks of the future. [Listen to this company’s audio interview.]

[ Top ]

Piedmont Pharmaceuticals (Greensboro, NC - www.piedmontpharma.com) Piedmont Pharmaceuticals is a specialty pharmaceutical company focused on human and veterinary therapeutics in select areas including parasitology and topical treatment of infection and inflammation. The company currently has two commercialized products and an advanced development program leverage innovative and proprietary transdermal drug-delivery technologies and unique modes of action.

[ Top ]

rPath (Raleigh, NC - www.rpath.com) rPath is a provider of Software Appliances for Linux Servers. They are the first company to provide software vendors with a comprehensive platform for delivering software appliances. Customers benefit from a no-hassle technology solution that eliminates the requirement to manage multiple maintenance streams, licenses, and service contracts.

[ Top ]

SCYNEXIS, Inc. (RTP, NC - www.scynexis.com) SCYNEXIS is a chemistry-focused partnering company leveraging our profitable chemistry service business to create product partnerships with our clients including leading pharmaceutical and biotechnology companies. SCYNEXIS' services business supports operations and overhead and provides some of the resources required for our partnerships.

[ Top ]

Xsira Pharmaceuticals, Inc. (RTP, NC - www.xsira.com) Xsira is a drug discovery and development company focused on GPCR targets for major CNS disorders using a balanced growth strategy consisting of a late stage pain management product and early stage leads derived from GPCR drug discovery capability. The late stage product candidate(Adenogesic™)is currently in Phase 2 clinical trials for perioperative analgesia. The initial early stage leads are novel CB1 antagonists for obesity and substance abuse. [Listen to this company’s audio interview.]

[ Top ]

Showcase Companies

Integrian, Inc. (Morrisville, NC - www.integrian.com) Integrian develops and manufactures mobile digital video solutions produced for the public safety and transportation markets, which are delivered through strategic partnerships and direct market channels. Customers use Integrian's technology to capture high-quality video in rugged, mobile environments and tag, transmit, archive and search video files for various security and law enforcement purposes.

[ Top ]

TranS1, Inc. (Wilmington, NC - www.trans1inc.com) TranS1 is a medical device company focused on minimally invasive surgical procedures to treat lower back pain. The company has developed a novel and proprietary percutaneous approach to access the lumbar spine. This transacral approach is the only surgical route to the lumbar spine which enables spine surgeons to access and treat discs S1 to L4, without the need to dissect or damage functional paraspinal soft tissue and bony structures.

[ Top ]