Ablatrics
Affinergy
BioPheresis Technologies
Chorus Systems
Curry Pharmaceuticals
Datacraft Solutions, Inc.
End II End Communications, Inc.
Noverant, Inc.
Polyglot Systems, Inc.
Red Pelican, Inc.
StrikeIron
WindChannel Communications, LLC
Xintek, Inc. (formerly Applied Nanotechnologies)
Alveolus
Bandwidth.com, Inc.
DarPharma, Inc.
KBI BioPharma, Inc.
Metabolon
Nuada Phramaceuticals, Inc.
Overture Networks
Piedmont Pharmaceuticals LLC
SCYNEXIS, Inc.
Serenex
Vital Source Technologies, Inc.
Ziptronix
(** note: these companies have been specifically selected to highlight the strengths of the greater Research Triangle region**)
APEX Analytix
Constella Group, Inc.
Click HERE to watch brief video interviews with several Venture ’04 presenting companies.
Ablatrics (Chapel Hill, NC) is an early stage medical device company focused on providing a complete minimally invasive, surgical treatment solution for Atrial Fibrillation. The company has developed a novel approach that reinvents radiofrequency ablation to create a cost-effective solution capable of curing atrial fibrillation.
Affinergy (RTP, NC - www.affinergy.com) develops “biological glues” which can selectively bond or repel specific materials and regulate biology at the surface of synthetic materials. Affinergy’s coatings will improve an existing product’s performance by “kick starting” biological processes such as bone ingrowth on orthopedic devices or repelling bacterial infections on medical devices. [ watch this company’s video interview ]
BioPheresis Technologies (Cary, NC) has developed a novel technology for treatment of cancer that has already been shown to result in promising anti-tumor responses in patients with several types of cancer, including breast, prostate, colon, lung, renal and metastatic melanoma. The process, which is based on removal of specific immuno-inhibitors via a medical device, is expected to gain regulatory approval faster than many drug based therapies. [ watch this company’s video interview ]
Chorus Systems (Durham, NC - www.chorussystems.com) develops enterprise software solutions for systems management and IT security. The company’s Uptime solution automates the detection, diagnosis, reporting and remediation of problems on servers and end user PCs. [ watch this company’s video interview ]
Curry Pharmaceuticals (RTP, NC) is a biopharmaceutical company that is developing novel drugs for cancer and inflammatory diseases based on the natural product curcumin. The company is assembling intellectual property to support the development of products for clinical testing and launch, initially for psoriasis and for major cancers.
Datacraft Solutions, Inc. (Durham, NC - www.datacraftsolutions.com) delivers process automation solutions to lean manufacturers through a secure Internet gateway, eliminating the need to install and maintain a complex IT infrastructure. Datacraft empowers small and mid-size companies with the competitive advantages of technology-driven, cost-effective process automation solutions.
End II End Communications, Inc. (Charlotte, NC - www.eiiecomm.com) is a network security and communications software company focused on bringing network equality to remote offices at the edge of a company’s wide area network. End II End’s patent pending Broadband Network Optimization (BNO) Technology maximizes the throughput of any broadband connection and integrates all essential network services on a single platform. [ watch this company’s video interview ]
Noverant, Inc. (Raleigh, NC - www.noverant.com) delivers systems and services to control and streamline the challenges of regulatory compliance for FDA regulated industries. The company streamlines compliance related activities and provides “on demand” information to provide immediate response to regulatory agency audits, thereby lowering the risk of non-compliance. Noverant further enhances its systems by focusing exclusively on the needs of industries regulated by the FDA.
Polyglot Systems, Inc. (Durham, NC – www.pgsi.com) develops and markets multilingual translation technology to the medical community, with an initial focus on emergency departments. The company’s “ProLingua 24/7” product enables healthcare professionals to communicate immediately and accurately with non-English speaking patients. This portable tool is designed to minimize the effect of language barriers in the Emergency Department so that healthcare professionals can focus on increasing their level of care for patients. [ watch this company’s video interview ]
Red Pelican, Inc. (Durham, NC – www.redpelican.net) has developed a Web-based tool that helps marketing/communications professionals plan, execute and monitor e-marketing promotion in support of their various campaigns and events. The company’s software works with targeted and adaptive email campaigns, Web-seminars, conferences, trade shows, local seminars as well as direct marketing call to action programs and surveys. [ watch this company’s video interview ]
StrikeIron (Durham, NC - www.strikeiron.com) is developing products and subscription-based online services that provide ease of use and increased productivity for the utilization of Web services. StrikeIron’s products allow anyone to quickly, and with minimal experience, take advantage of Web services for access to information, integration with existing applications, and the development of new applications. [ watch this company’s video interview ]
WindChannel Communications, LLC (Raleigh, NC - www.windchannel.com) supplies three market segments with a viable alternative to legacy wireline systems: (1) Enterprise Solutions, which include internet connectivity (primary and redundant), and Metro building to building connectivity; (2) Visitor Based Networks, which include Hospitality, MDU, and Medical; and (3) Rural Initiatives, which deliver broadband services to areas with no current options. [ watch this company’s video interview ]
Xintek, Inc. (formerly Applied Nanotechnologies) (Chapel Hill, NC www.applied-nanotech.com) develops carbon nanotube (CNT) based field emission electron source for x-ray and displays. Compared to conventional hot source x-rays, field emission electron source can save energy, significantly shrink the size of devices, produce higher resolution (in case of x-ray), enable pulsed x-ray, and reduce the cost of x-ray and display manfuacturers.
Alveolus (Charlotte, NC www.alveolus.com) is designing next generation stent technology and delivery device applications in the emerging field of non-vascular stenting. Alveolus has received FDA and CE approval, and the company is set to market and sell their tracheobronchial stents in the United States and Europe. In addition, the company expects regulatory approval on the worlds first removable self expanding stent that can be placed with direct visualization (no fluoroscopy or x-ray required) thus potentially eliminating many of the current complications with existing stent technology.
Bandwidth.com, Inc. (Cary, NC – www.bandwidth.com) is a “meta-carrier” that contracts with internet service providers in advance for volume purchases and guaranteed availability. The firm’s carrier partners include ATT, Worldcom, Qwest, Sprint, Verizon, SBC and more than 10 others enabling the company to market connectivity from DSL to T3s to both businesses and consumers. The company’s Web site and systems allow customers to make informed judgments about their options by providing easy access to the selection, pricing and availability at any time. [ watch this company’s video interview ]
DarPharma, Inc. (Chapel Hill, NC - www.darpharma.com) is a pharmaceutical company focused on developing dopamine receptor agonists for neurological and psychiatric diseases, including Parkinson’s disease, schizophrenia, cognition and memory disorders and autism. These neurologic and psychiatric diseases are the result of imbalances in the neurotransmitter dopamine, which makes up more than 50% of the neurotransmitters in the brain. [ watch this company’s video interview ]
KBI BioPharma, Inc. (Durham, NC www.kbibiopharma.com) is a contract manufacturer of biologic therapeutics for the pharmaceutical industry using conventional technology. From this conventional platform, KBI BioPharma also has proprietary Centrifugal BioReactor (CBR) technology that, once commercialized, will allow continuous production of uniform higher quality product at significantly lower capital and operating costs.
Metabolon, Inc. (Durham, NC - www.metabolon.com) is a leader in the application of metabolomics, a new and powerful scientific approach for the discovery, development, and repositioning of drugs. The company measures the total content of biochemicals in the cell or body fluid and displays results in physiological context by mapping them to metabolic pathways. Metabolon's technology will work to uncover the underlying causes of disease. [ watch this company’s video interview ]
Nuada Pharmaceuticals, Inc. (Durham, NC - www.nuadapharma.com) is a chemistry-driven drug discovery company using its proprietary chemistry technology platform, medicinal chemistry expertise and preclinical networks to discover new clinical candidate molecules for both internal programs and collaborative projects. The company’s platform is “pan-therapeutic” which allows Nuada to pursue a large number of viable drug candidates.
Overture Networks (Morrisville, NC - www.overturenetworks.com) addresses three critical problems facing telecom carriers deploying metro networks today: how to increase revenues, how to decrease costs, and how to migrate to next-generation networks. With Overture’s platform, carriers can move towards a data-optimized network that can keep pace with the increasing need for intelligence and speed at the edge of the network.
Piedmont Pharmaceuticals LLC (Greensboro, NC - www.piedmontpharma.com) identifies underserved markets and creates pharmaceuticals that offer differentiated advantages through its drug delivery and proprietary formulation technologies. The company’s lead human pharmaceutical candidate is a head lice treatment that uses a non-toxic formulation, without any of the classical insecticides traditionally used in lice treatments.
SCYNEXIS, Inc. (RTP, NC www.scynexis.com) is a chemistry-focused drug discovery and development company with expertise and capabilities across the entire drug development lifecycle, including lead discovery, lead optimization, cGMP manufacturing and radiochemistry. SCYNEXIS hopes to discover and develop small molecule drugs and drug candidates in partnership with leading pharmaceutical and biotechnology companies, and to grow and sustain a profitable chemistry contract research business unit to support operations.
Serenex (Durham, NC - www.serenex.com) Serenex is a drug discovery company built around a high throughput, compound-centric chemoproteomics technology platform. The company has the ability to screen compounds against as many as 4,000 potential targets simultaneously. As well as having an internal discovery pipeline, the company has discovery collaborations with several large pharma and biotech companies including GSK, Lilly, J&J, Roche, Chiron, Aventis and other major pharmaceutical company.
Vital Source Technologies, Inc. (Raleigh, NC – www.vitalbook.com) provides platform solutions and digital content to students and faculty in education markets. Vital Source offers a suite of software and services for graduate and professional schools, undergraduate schools, and elementary and secondary schools. The company delivers education materials (such as textbooks, course packs and videos) in a software solution that works to reduce study and research time, while delivering better student performance. [ watch this company’s video interview ]
Ziptronix (Morrisville, NC – www.ziptronix.com) has developed special bonding processes enabling three-dimensional integrated circuits that are smaller, faster, cheaper and consume less power. These unique bonding processes have quantified benefits compared to the other methods the industry is exploring to tackle the issues of speed, performance, cost and power consumption. [ watch this company’s video interview ]
(** note: these companies have been specifically selected to highlight the strengths of the greater Research Triangle region**)
APEX Analytix (Greensboro, NC - www.apexanalytix.com) provides audit and cost recovery software and services designed to detect, recover and prevent errors related to corporate expenditures. The company’s product enables clients to assess and understand the weaknesses in their procurement and payables systems, to implement an overpayment and duplicate payment prevention tool and to better manage relationships with suppliers.
Constella Group, Inc. (Durham, NC - www.constellagroup.com) is a leading provider of professional health services worldwide. Constella’s three business units - Health Sciences, Clinical Informatics and Health Strategies - conduct health research and provide a variety of technical, professional and strategic consulting services to help pharmaceutical, biotechnology and government clients identify and solve problems affecting human health. [ watch this company’s video interview ]