ADAC Lab, NCSU (Raleigh, NC, www.adac.ncsu.edu/iSpace1/home.html) ADAC Lab has developed Intelligent Space (iSpace), a relatively new concept to effectively use distributed sensors, actuators, robots, computing processors and information technology over communication networks. iSpace is a large scale Mechatronics System by integrating sensors, actuators and control algorithms in a communication system using knowledge from various engineering disciplines such as automation and control, hardware and software design, image processing, communication and networking.

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Bioptigen (Durham, NC, www.bioptigen.com) Bioptigen is advancing 3D optical imaging systems for pre-clinical pharma, biotech and biomedical applications. Bioptigen's non-invasive designs are uniquely suited to in vivo, volumetric, real-time imaging of small animal models at tissue-level resolution. Bioptigen's technology significantly reduces the need for surgical histology in pre-clinical drug efficacy and toxicology testing and offers unmatched dynamic imaging capabilities for functional genomics and tissue engineering research. [ Listen to this company's audio interview. ]

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Bright View Technologies, Inc. (Durham, NC, www.brightviewtechnologies.com) Bright View Technologies is developing light management products that are incorporated into visual display products like rear projection televisions, front projection displays and LCD displays. These products are enabled by Bright View's unique and proprietary platform technology, X-LAMP's, which provides production capabilities that do not exist elsewhere in the market.

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Centice Corporation (Raleigh, NC, www.centice.com) Centice develops next generation optical sensors for medical diagnostics and chemical analysis applications. Centice proprietary sensor technology samples and processes up to 1,000 optical channels simultaneously to provide unparalleled measurement sensitivity and signal quality. These superior performance characteristics are ideal for in vitro and in vivo blood analysis.

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Clinication, Inc. (Raleigh, NC, www.clinication.com) Clinication™ provides secure, web-based patient/clinician communication and disease-management tools that encourage adherence, monitor status and allow a dynamic exchange of information between the healthcare provider and the patient, promoting cost-containment, increased revenues, improved outcomes and an effective care-management partnership. [ Listen to this company's audio interview. ]

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Emergent Game Technologies (formerly NDL) (Chapel Hill, NC, www.ndl.com) Game developers using Emergent's Gamebryo 3D graphics tools and engine focus their energy and resources on what is important: creating great gameplay and compelling 3D content. Emergent's Gamebryo reduces risk and saves time and money for game developers developing titles for the PC, PlayStation2, Xbox, Gamecube and the next generation consoles as well: Xbox 360 and Playstation3. More than 100 titles have shipped or are in development, including blockbuster hits that have won numerous industry awards. Beyond games, Gamebryo has been used for simulation and training, architectural walkthroughs, and medical training.

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Emu Software (Durham, NC, www.emusoftware.com) Emu Software's NetDirector sets the standard for granular, GUI-based, on-the-fly server application management. Make changes across multiple servers simultaneously, schedule changes for later and rollback any change at any time to any previous configuration. NetDirector provides IT executives with unparalleled visibility and control over their Linux assets.

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ETemplate Systems (Raleigh, NC, www.etemplatesystem.com) ETemplate System's ETemplate Photo technology is a 3 dimensional measurement system utilizing digital photography. Using triangulation, ETemplate collects data from medium scale objects, creating CAD (computer aided design) compatible geometry. The intelligent processing of the data provides visual analysis of both the measured object and the CAD design within the digital photograph. [ Listen to this company's audio interview. ]

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Field2Base (Morrisville, NC, www.Field2Base.com) Field2Base provides a mobile data communications system that is applicable to any industry that needs to automate the capture and flow of information between the field and office. We utilize the Tablet PC as the field device enhanced with our software and communications system to provide mobility, wireless communications, and handwrite recognition capability to field operations. Field2Base enables mobile data communications for any type of data, including annotated digital photos, annotated CADs, sketches, email, forms, fax, etc. anywhere a cell phone operates or wireless (WiFi) networking is available. Field2Base has integrated the data capture function with the communications capability to provide an ease of use solution in the field. [ Listen to this company's audio interview. ]

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IBM Extreme Blue (RTP, NC, www.ibm.com/extremeblue) IBM's Extreme Blue Program is developing a prototype Autonomic Workplace Client Technologies (WCT) platform, which applies autonomic computing principles and technologies to detect, analyze and respond to run-time failures in production applications installed on the WCT platform, It will provide multilevel self-management by providing local autonomic capabilities at the client and holistic autonomic function at the server. This eases problem management of a large base of deployed clients through problem aggregation, consolidated reporting and system wide corrective actions. [ Listen to this company's audio interview. ]

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InfoStrength (Raleigh, NC, www.infostrength.com) The InfoStrength Smart Enterprise Suite is a web-based application solution specifically designed to address the unique needs of biotechnology, pharmaceutical and life science companies. The InfoStrength Smart Enterprise Suite delivers extensive collaboration functionality that includes project/process management, document management, tools for strategic decision making and long-term knowledge preservation. The InfoStrength solution enables unlimited customizable growth that does not require software development or IT expertise at a price point that small to mid sized organizations can afford. [ Listen to this company's audio interview. ]

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Lab Escape, Inc. (Asheville, NC, www.labescape.com) Lab Escape develops data visualization components for integration into enterprise applications, enabling users to identify trends, problems and opportunities lying hidden in increasingly large and complex data stores. Our customers include medium and large enterprises in industries ranging from financial services to healthcare to government research.

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Live Cargo, Inc. (Greensboro, NC, www.livecargo.com) Live Cargo, Inc. is a developer of proprietary, patent-pending software used for encryption and file management of digital content. The company's suite of software modules include secure file transfer, remote storage, collaboration and data archiving. These solutions improve and optimize processes associated with managing documents and digital media, referred to as electronic “packages,” over the Internet. [ Listen to this company's audio interview. ]

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MercuryMD, Inc. (Durham, NC, www.mercurymd.com) MercuryMD is a private, healthcare-focused software company that provides hospitals with mobility solutions to improve clinical workflow and operational efficiencies while enhancing patient care. Its MData® CareFocus application is a profiling engine that utilizes clinical logic to prospectively identify high-risk patient populations; it applies data profiles to current patient information and segments patients matching these profiles into separate lists available to clinicians on their PDA, smartphone or tablet PC.

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MyBode, Inc. (Durham, NC, www.mybode.com) MyBode's BestHomePro software uses patented matching technology in combination with lead management software to greatly enhance the homes search process for Realtors and consumers. The software suite displays properties in the order of best fit and automatically alerts buyers and Realtors to new properties each day. [ Listen to this company's audio interview. ]

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PROOF-it-ONLINE (Cary, NC, www.proofitonline.com) PROOF-it-ONLINE created a multitenanted hosted application which creative professionals - printers, publishers, advertising agencies, graphic designers and marketing staff - in small through large companies employ to get the work they create proofed, approved or signed-off-on by clients or colleagues. If you've had a brochure created or bought a display ad you've experienced the headaches and delays of going back and forth in the creation process with copy, design and layout. The online service solves the approval problem and extends beyond traditional email delivery of PDF's to offer tracking, versioning and archiving as well as virtual routing tools. Clients see proofs in color, they can mark/edit proofs in their browser, easily approve proofs and the designer receives the approval in minutes.

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Saffron Technology (Morrisville, NC, www.saffrontech.com) Saffron Technology has developed SaffronWeb technology, a software that learns from you, with you and for you. SaffronWeb automatically reads and connects all the "dots" during the real-time arrival of structured and unstructured data. Providing analytic discovery rather than simple search, SaffronWeb can then provide relevant and novel answers to queries that users' didn't even know to ask. As individual users make discoveries (and decide to publish them), SaffronWeb also answers queries by recommending other users and their relevant discoveries. This easy-to-use system of discovery and sharing can help any enterprise that wants to allow all its employees to unlock the hidden patterns in all its data.

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SciQuest, Inc. (Morrisville, NC, www.sciquest.com) SciQuest provides supplier management and procurement automation solutions that help customers gain greater visibility and control over their spending. Through its supplier network, SciQuest aggregates detailed supplier content and enables supplier connectivity, providing a purchasing experience that drives user adoption and contract compliance. By leveraging SciQuest's expertise in on-demand content management and procurement automation, customers can rapidly improve efficiency and capture unrealized savings.

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Sensory Analytics, LLC (Greensboro, NC, www.sensoryanalytics.com) Sensory Analytics has developed a suite of innovative non-contact measurement and process control systems that help manufacturers reduce their scrap, rework and labor hours from both production and non-conformance paperwork. By applying these patented solutions in-line, on a stand alone basis or through new handheld devices, manufacturers can gain real-time production and quality data critical for lean manufacturing and other advanced quality initiatives. Market applications include medical, aerospace, electronics, converting as well as home and building materials.

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Stonewall Networks (Cary, NC, www.stonewallnetworks.com) Stonewall's Cornerstone technology is an advanced multi-vendor security policy manager that provides consistent and effective end-to-end modeling and deployment of network security policies. Its main features and advantages include the innovative XML-based core engine, multi-vendor device support, topology-based graphical policy and service management, as well as the provisioning, auditing, enforcement, analysis and recommendation of network security policies. In addition, Cornerstone is capable of integrating with existing Security Event Managers, Vulnerability Assessment tools and Issue/Incident Management applications, providing a complete security platform.

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TransLoc Inc. (Raleigh, NC, www.transloc-inc.com) TransLoc specializes in the collection and presentation of real-time transit information. Our technology continuously displays the location of vehicles and animates their motion against a detailed map of recognizable buildings and landmarks. Already, our technology is helping public transit riders save time, stay safe and have more control over their schedules while enabling transit administrators to manage their fleets with unprecedented clarity.

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VirtuosoWorks, Inc. (Greensboro, NC, www.notionmusic.com) VirtuosoWorks is the creator of NOTION™ - the first integrated software to take music composition from notation to instant concert quality playback. Featuring the London Symphony Orchestra at Abbey Road Studios, NOTION™ substantially reduces cost and delivery time for industries that depend on the creation of original music (such as film and broadcast) by generating realistic soundtracks directly from the composer's notation. For industries that rely on live performance of existing musical works (such as musical theatre, ballet, and opera) the technology can significantly reduce cost by supplementing or replacing live musicians with interactive orchestral accompaniment.

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ZellComp, Inc. (Durham, NC, www.zellcomp.com) A significant percentage of highway bridges in the United States have been classified as deficient; these structures are operating beyond their projected life expectancies and are increasingly subjected to weights, loads, and traffic volumes exceeding the limits designed for at the time of installation. In response to the government and industry challenge of developing new technologies rather than simply continuing to patch the existing network, ZellComp has designed a patented, innovative prefabricated fiber-reinforced composite decking system. The ZellComp system is lightweight and long lasting, but, in addition, ZellComp's unique two-part design, resulting in an “open” system, is less expensive to manufacture, is easier and faster to install, inspect and repair, and offers the additional advantage of utilizing mechanical fasteners, avoiding the construction difficulties encountered by other composite decks tha are bonded together with adhesives during installation.

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ZumaTek, Inc. (Durham, NC, www.zumatek.com) This technology provides a shift away from standard mammography paradigm as it provides a 3D image of the breast, chest wall and lymph nodes using well accepted nuclear medicine SPECT or PET and X-ray CT, resulting in both functional and structural images of the breast and surrounding regions without any breast compression. The new breast scanner imaging system detects early signs of breast cancer by combining dedicated functional and structural imaging in a comfortable, patient friendly setting. [ Listen to this company's audio interview. ]

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